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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease polycystic ovary syndrome
Comorbidity C0002453|amenorrhea
Sentences 9
PubMedID- 23939500 Most cases of secondary amenorrhea can be attributed to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, or primary ovarian insufficiency.
PubMedID- 22723725 Stein and leventhal initially described polycystic ovarian syndrome (pcos) with associated amenorrhea in 1935.1 they also described a strategy called an ovarian wedge resection that seemed to be effective in treating the associated infertility.
PubMedID- 25963777 However, a polycystic ovary syndrome (with secondary amenorrhea, polycystic ovaries, and hirsutism) was diagnosed.figure 1magnetic resonance imaging shows a slight but atypical age-related frontoparietal and cerebellar atrophy.figure 2[18f]fluorodeoxyglucose positron emission tomography (fdg-pet) showed a mild, borderline significant cerebellar hypometabolism.
PubMedID- 23081959 Results: the endometrium was thinner in pcos with oligo-amenorrhea compared to controls, also after adjustments for age and bmi (adjusted p = 0.043).
PubMedID- 23355936 She was affected by hyperinsulinism, hyperandrogenism, amenorrhea, ultrasound signs of polycystic ovarian syndrome (pcos), hypertension with left ventricular hypertrophy as co-morbidities.
PubMedID- 22562579 pcos is associated with oligomenorrhea or amenorrhea, androgen excess, and a high incidence of uterine endometrial hyperplasia.
PubMedID- 25246891 The symptoms of ncah include early pubarche, hirsutism (60%), oligomenorrhea or amenorrhea with polycystic ovaries (54%), and acne (33%) (5, 6).
PubMedID- 24405081 The objective of the current review was to provide an overview on the use of metformin and/or ocs for the management of oligo-amenorrhea in adolescents with pcos underlining their potential risks and benefits in order to help the clinician to choose the best patients' tailored treatment.
PubMedID- 24693495 Secondary amenorrhea was due to polycystic ovary syndrome (48.4%, 523/1,080); premature ovarian insufficiency (14.0%, 151/1,080); and nutrition-related hypogonadotropic hypogonadism (8.3%, 90/1,080).

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